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Resveratrol - A05

Deep wrinkles
  • Indications

    • Resveratrol pure Active is especially indicated for deep wrinkles. Over time, the skin's support tissue loses its density and wrinkles deepen. This is caused mainly by the repeated attacks of free radicals on the various constituents of the skin.
      It will be highly valued for mature skin presenting occasional blemishes (shine and small spots).

  • Learn more

    • Present in vine shoots, Resveratrol is a powerful anti-ageing molecule. In addition to protecting the skin from damage caused by free radicals, this active increases cell lifespan by stimulating the production of sirtuins, longevity proteins. The number and surface area of wrinkles are thus reduced.

RESVERATROL : Complementary products

Directions for use

For the entire face: shake before use and apply 4 drops to the entire face, massage until completely absorbed, concentrating on the wrinkles.

This product is chestnut-coloured, reflecting the natural colour of Resveratrol, combined with the IN-SKIN® system at its effective dose. Once applied to the skin, the product is instantly absorbed, leaving no trace of colour.

LONG-TERM TREATMENT : use twice a day, morning and night, for at least 2 months.
For an effect on deep wrinkles, a long-term treatment is necessary.
To ensure sufficient supplies of the product throughout treatment, we recommend buying 2 bottles of Resveratrol pure Active.

INTENSIVE TREATMENT combining several pure Actives:
- For a regenerating effect in depth: use Resveratrol pure Active in the morning and Hyaluronic Acid pure Active at night. Repeat if necessary.

As an ideal complement, we recommend applying a Biomimetic skincare after the pure Active, suited to the nature and day-to-day needs of your skin.
Suggestion for the morning: Firming lifting care.
Suggestion for the evening: Redensifying regenerating care.

Efficacity proven

Scientific studies and recognized publications show that Resveratrol acts at various levels in the skin:



Protection of cells and skin tissue
Resveratrol protects cells and skin tissue from damage caused by free radicals. An in-vitro test has thus demonstrated its ability to prevent 95% of lipid peroxidation.
Better protected, the skin can better defend itself against environmental damage and ages less quickly.


Effect on cell differentiation
Resveratrol acts on cell differentiation in skin cells (retinol-like effect). Skin renewal is stimulated.


Effect on sebum regulation
An in-vitro test has revealed a targeted effect on sebum production to normalize combination skin or occasional blemishes (shine, spots).


Optimization of cell lifespan
Resveratrol optimizes cell lifespan by stimulating the production of the longevity proteins, sirtuins. This has been demonstrated in vitro on aged fibroblast cultures.



Targeted effect on wrinkles
A clinical study conducted on 20 women aged between 49 and 69, presenting deep wrinkles, yielded the following results:

  • the surface area of wrinkles is reduced by 23%
  • the number of wrinkles is reduced by 71%
  • 80% of the women saw an improvement in the appearance of their skin in 56 days.


References and proofs of effectiveness of Resveratrol (clinical studies, bibliographies and expert opinions)

PURE ACTIVE : **Vine shoot extract with guaranteed content in Resveratrol monomers and oligomers [INULIN VITIS VINIFERA (GRAPE) VINE EXTRACT]
The bottle contains 70 mg of pure Active.
This is the quantity needed so that each application done according to the directions for use provides the skin with the effective dose recommended by scientific studies.

Proven effectiveness

PATENTED IN-SKIN® SYSTEM : to treat the skin exactly where it is needed, Resveratrol pure Active is combined with a unique delivery system.
It is totally absorbed by the skin so that it can interact with the cells in depth.


*eau isodermique / isodermic water.
Scientific history

Resveratrol is a polyphenol naturally present in red fruits such as grapes or blackberries and in certain plants such as eucalyptus and vine shoots.

It was discovered in Japan in the 1980s when a team of researchers identified it in the dried roots of Polygonaceae. These roots had been used for centuries in traditional Japanese and Chinese medicine to treat various complaints (allergies and skin inflammations).

Its powerful anti-free radical effect was then revealed by several researchers.

It has received particular attention because it is part of the enigma referred to as the French paradox: in south-west France, in spite of a high consumption of animal fats, levels of cardiovascular disease remain astonishingly low. The explanation comes from consumption associated with Resveratrol, which is found naturally in wine!

Indeed, Resveratrol helps to regulate cholesterol levels. It is now highly prized as a food complement.

For some years, Resveratrol has also been employed in cosmetics formulations. In addition to being one of the most powerful antioxidants on the market, it has shown that it increases cell lifespan. Indeed, it acts specifically on sirtuins, small molecules discovered in 2000, that guarantee the integrity of cell DNA.

A study has revealed that, out of more than 20,000 Actives tested, Resveratrol was the one that had the greatest ability to stimulate production of these sirtuins.

Its beneficial effects on the skin are still undergoing a considerable amount of research.

Origin / Video

The vine shoots selected by ETAT PUR come from the heart of the Bordeaux wine-growing area. They are recovered during the annual pruning of the Merlot and Cabernet Franc grape varieties.

The active fraction sought is then gradually extracted, concentrated and purified using a very specific, patented process.

We thus obtain a vine shoot extract with a guaranteed Resveratrol content (monomers and oligomers).

The video

The quality control of this ingredient is handled by DIPTA, the research centre and inspection laboratory for the ETAT PUR, BIODERMA and ESTHEDERM brands in Aix-en-Provence.

All details concerning the origin and quality of this pure Active are filed by ETAT PUR and can be accessed by all inspection bodies, which guarantees us total confidentiality in data processing.

Opinion of the dermatologist

Resveratrol - Pure Active A05

Resveratrol is an anti-ageing molecule with considerable potential thanks to its powerful antioxidant and anti-free radical activity and its "retinol-like" action. Its good tolerance profile is also an advantage. Indeed, the use of topical tretinoin (vitamin A acid), an anti-ageing molecule of choice in dermatology, whose efficacy is proven, is limited by problems of poor tolerance, which means looking for other effective and better tolerated molecules.

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