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Glabridin - A71

Uneven complexion
  • Indications

    • Glabridin pure Active is indicated for hyperpigmented areas and dark spots. It is especially recommended to alleviate the mask of pregnancy and reduce marks related to strong UV exposure.

  • Learn more

    • Glabridin has depigmentation and lightening properties. It inhibits the production of melanin, the pigment responsible for the colouring of the skin.

GLABRIDIN : Complementary products

Directions for use

For the entire face, the upper chest and the hands: apply 2 to 4 drops depending on the area affected.

LONG-TERM TREATMENT : use twice a day. Minimum period of treatment: 2 months.

INTENSIVE TREATMENT : combining several pure Actives:
- If the complexion is dull and lacking in radiance: use Glabradin pure Active for 3 weeks in the morning and Citric Acid - AHA pure Active at night. Repeat the treatment if necessary.

After application, do not expose your skin to the sun. If you do, use suitable sun protection.

As an ideal complement, we recommend applying a Biomimetic skincare after the pure Active, suited to the nature and day-to-day needs of your skin.
Suggestion for the morning: Light moisturizing cream or Melting moisturizing cream.
In cases of sun exposure: apply a sun product with a higher protection rating (SPF 30 to 50).

Efficacity proven

Scientific studies and recognized publications show that Glabridin titrated extract acts at various levels in the skin:



Inhibition of melanogenesis
Glabridin would inhibit the synthesis of melanin by inhibiting the tyrosinase enzyme. Glabridin is a lightening agent that offers an excellent tyrosinase-inhibiting effect and very good depigmentation power.



Lightening properties
Various studies have demonstrated the effectiveness of Glabridin on melasma with slight irritation that disappears after treatment.

References and proofs of effectiveness of Glabridin (clinical studies, bibliographies and expert opinions)

PURE ACTIVE : **Liquorice root extract with guaranteed Glabridin content [GLYCYRRHIZA GLABRA (LIQUORICE) ROOT EXTRACT]
The bottle contains 2.5 mg of pure Active.
 This is the quantity needed so that each application done according to the directions for use provides the skin with the effective dose recommended by scientific studies.
Proven effectiveness

PATENTED IN-SKIN® SYSTEM : to treat the skin exactly where it is needed, Glabridin pure Active is combined with a unique delivery system.
It is totally absorbed by the skin so that it can interact with the cells in depth.

Scientific history

Glabridin is the main component of the hydrophobic fraction of Liquorice extracts.

The history of liquorice dates back several centuries. It was already mentioned in Chinese treatises on traditional herbalism and in the papyrus scrolls of ancient Egypt. Traditional Chinese medicine also recommended using liquorice root for treating various complaints.

Liquorice root contains numerous polyphenols, Glabridin being the main component. It has an antioxidant effect, destroying free radicals, and it inhibits melanogenesis, the synthesis of melanin.

Glabridin is used in cosmetics for its lightening and depigmentation properties.

Origin / Video

This pure Active comes from a liquorice root extract. ETAT PUR has selected a Chinese producer committed to a responsible, environmentally friendly approach.

The active fraction sought is gradually extracted from the liquorice roots to obtain a liquorice extract containing more than 40% Glabridin.

>> The video

The quality control of this ingredient is handled by DIPTA, the research centre and inspection laboratory for the ETAT PUR, BIODERMA and ESTHEDERM brands in Aix-en-Provence.

All details concerning the origin and quality of this pure Active are filed by ETAT PUR and can be accessed by all inspection bodies, which guarantees us total confidentiality in data processing.

Opinion of the dermatologist

Glabridin - Pure Active A71

Glabridin is a molecule whose melanogenesis-inhibiting effect (production of melanin, which is the brown pigment in the skin) is significant and proven. It is therefore a depigmentation active with considerable potential.

It should be borne in mind, however, that hyperpigmentation is still difficult to treat in dermatology, particularly when the pigment is present deep within the skin. There should therefore be no hesitation in combining several depigmentation actives, acting on melanogenesis in various ways to optimize the results. Combination with Arbutin pure Active or kojic acid (shortly available on the ETAT PUR website) may thus be proposed. If the results are insufficient, consult your dermatologist, who will be able to discuss other solutions with you (preparations containing hydroquinone, peeling, laser pigment or flash lamp treatment).

Finally, I can never say often enough that, if you have problems with dark spots and hyperpigmentation, the sun is your worst enemy; solar eviction therefore and applications of high factor sun cream several times a day to provide protection against UVBs (SPF 50+) and UVAs during months when the sun is strong (from April/May to October).

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