For the entire face: apply 4 drops to clean, dry skin.
INITIAL TREATMENT : use morning and night for 1 week.
INTENSIVE TREATMENT combining several pure Actives:
- If the skin is fine and fragile: use Enoxolone pure Active for 1 week in the morning and Mimosa tenuiflora pure Active at night. Then continue using Mimosa tenuiflora pure Active for 3 weeks morning and night.
- If the skin is also rough and flaky: use Enoxolone pure Active for 1 week and D-Panthenol pure Active one after the other, morning and night.
- If the skin is dehydrated and tight: use Enoxolone pure Active for 1 week and Aloe vera pure Active one after the other, morning and night.
As an ideal complement, we recommend applying a Biomimetic skincare after the pure Active, suited to the nature and day-to-day needs of your skin.
Suggestion: Soothing lipid-replenishing care.
Scientific studies and recognized publications show that Enoxolone, also called glycyrrhetinic acid, acts at various levels in the skin:
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Soothing effect on fragile skin By inhibiting the enzymes responsible for the production of these mediators, Enoxolone reduces irritant reactions and calms and soothes the skin. |
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Similar effect to corticoids In vivo, its effectiveness has been demonstrated on patients suffering from atopic dermatitis: significant reduction of erythema, oedema and itching. |
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Protective effect against redness caused by UV rays Enoxolone, by reducing the synthesis of histamine, rapidly soothes the skin and enables it to alleviate its irritant potential. |
Proven effectiveness

It is totally absorbed by the skin so that it can interact with the cells in depth.
The soothing and tonifying properties of Liquorice, known for several hundred years, have been learnt from the basics of Chinese medicine and its treatises on herbalism. We also find proofs of its ancestral use in the papyrus scrolls of the Egyptians.
Liquorice extracts, rich in Enoxolone, are now commonly used in phytotherapy and medicine as an anti-inflammatory. Enoxolone is an active pharmaceutical agent found in several forms of medication.
Locally applied, Enoxolone is used principally in the symptomatic treatment of moderate and not superinfected inflammatory incidents such as atopic eczema, solar erythema, seborrhaeic dermatitis, pruritis vulvae or insect stings.
In dermatology, Enoxolone is known to soothe reactive skin and reduce redness and burning sensations.
Enoxolone is a natural molecule found in large quantities in the roots of Liquorice, Glycyrrhiza glabra (L.).
The Liquorice selected by ETAT PUR comes from China. Several environmentally friendly producers guarantee a constant supply of the fresh plant.
The active fraction sought is gradually extracted from the liquorice roots, concentrated and purified until Enoxolone more than 98% pure is obtained.
The quality control of this ingredient is handled by DIPTA, the research centre and inspection laboratory for the ETAT PUR, BIODERMA and ESTHEDERM brands in Aix-en-Provence.
All details concerning the origin and quality of this pure Active are filed by ETAT PUR and can be accessed by all inspection bodies, which guarantees us total confidentiality in data processing.
Opinion of the dermatologist
Enoxolone - Pure Active A43
Enoxolone or glycyrrhetinic acid has anti-inflammatory properties equivalent to a low-activity local corticoid like hydrocortisone.
This concentration [280] is indicated for treating the majority of acute inflammatory manifestations on the face such as: sunburn, erythema (redness) after a dermatological procedure (laser, peeling, etc.), post-depilation erythema or shaving, insect bites, for example.
If the skin on your face is sensitive and chronically reactive, choose Bisabolol pure Active or Oat pure Active, which you can use for in depth treatment over a long period.